Block I | Methods

This session introduces foundational methods for constructing, evaluating, and interpreting genetic and epigenetic measures in population research. Presenters will cover ethical considerations in polygenic score research, innovations in ensemble PGI construction from GWAS summary statistics, and novel approaches for disentangling genetic and environmental contributions using sibling quasi-experimental designs. Together, these talks offer conceptual and technical grounding for interdisciplinary researchers working at the intersection of genetics and the social sciences.

Jean Cadigan | University of North Carolina at Chapel Hill

Between Promise and Risk: Reflections from Researchers Using Polygenic Scores for Social Traits


Jonathan Beauchamp | George Mason University

Nature, nurture, and socioeconomic outcomes: New evidence from sib pairs and molecular genetic data


Qiongshi Lu | University of Wisconsin-Madison

One score to rule them all: regularized ensemble polygenic risk prediction with GWAS summary statistics


Patrick Turley | University of Southern California

Two Novel Methods Greatly Increase the Precision of Sibling-based Heritability and Partitioned Heritability Estimates


Jeffrey Swigert | University of Southern California

Genomic-Relatedness Matching Expands Population Coverage, Improves Power and Reduces Bias in Genetic Association Analyses


Sarah M. Merrill | University of Massachusetts Lowell

Impact of age-related changes in buccal epithelial cells on pediatric epigenetic biomarker research


Block II | Genomic Economics

This session explores how genetic predispositions interact with social and institutional environments to shape economic outcomes. Talks examine the causal effects of personality traits on wealth, the influence of children’s genetics on parental finances, and the moderating role of education and labor market structures on genetic returns. Together, these presentations illustrate the bidirectional and policy-relevant ways that genes and environments jointly produce economic inequality.

Joakim Ebeltoft | University of Oslo

Child genetic effects on parent finances in the Norwegian welfare state


Leandro Carvalho | University of Southern California

Personality Traits, Human Capital Formation & Economic Behavior: Exploiting Random Genetic Variation to Study the Causal Effects of Personality Traits


Giorgia Mezzetti | University of Bologna

The Role of Gene–Environment Interaction in the Gender Wage Gap


Pietro Biroli | University of Bologna

Genetically Informed Estimation of Marginal Returns to Education


Yannick Reichlin | Bocconi University

The Heterogeneous Impact of Automation on Older Workers


Tomeu López-Nieto Veitch | University of Bologna

The Causal Effects of Educational Policies on Assortative Mating


Block III | Ancestry, Environment & Genetic Risk

This session explores how genetic ancestry and social context shape health and behavioral outcomes. Talks examine patterns of assortative mating, cardiometabolic risk across ancestry groups, and gene-environment interactions involving BMI, obesity, and aging resilience. Collectively, the presentations underscore the importance of incorporating population structure and environmental variation when interpreting genetic influences on complex traits.

Luyin Zhang | Princeton University

Genetic Ancestry-Based Assortative Mating within the U.S. Black and Hispanic Populations


Silvia Barcellos | University of Wisconsin-Madison

The Effects of African Genetic Ancestry Proportion on Cardiometabolic Health Outcomes in the AllofUs Research Program


Dalton Conley | Princeton University

Children’s genetic liability for psychopathology and parental health behaviors


Shutian Liu | Imperial College London

Socioeconomic Disparities in Adolescent BMI: Disentangling Genetic and Environmental Pathways Using the UK Millennium Cohort Study


Tadeja Gracner | University of Southern California

Early-life Sugar Restrictions Narrow Genetic Disparities in Adult Obesity


Nicole Gladish | Stanford University

Disentangling Genetic and Environmental Contributions to Longevity in the Nicoya Population


Block IV | Societal Epigenetics

This session explores how structural and environmental factors, including ancestry, pollution, healthcare access, incarceration, and military service, influence biological aging through epigenetic pathways. Presenters highlight disparities in epigenetic clock performance across populations and demonstrate how public policies and institutional exposures shape molecular aging. Together, these talks emphasize the need for context-aware approaches in epigenetic research.

Gillian Meeks | UC Davis

Common DNA Sequence Variation Influences Epigenetic Aging in African Populations


Amanda Kurowski | University of British Columbia

Socioeconomic Determinants and Biological Aging: Exploring the Potential Mediating Role of Environmental Exposures in the Canadian Longitudinal Study on Aging


Nicolau Martin-Bassols | University of Bologna

The Causal Effect of Medicaid and CHIP on Epigenetic Ageing


Francesco DiRienzo | University of Cincinnati

The Association Between Arrest Experiences and Biological Aging in Childhood and Adolescence: A Longitudinal Analysis


Block V | Adversity Epigenetics

This session examines how early-life adversity, trauma, chronic stress, and resilience shape biological aging through epigenetic mechanisms. Talks explore the impacts of violence, perceived stress, and adverse childhood experiences, as well as intergenerational transmission and the dynamics of aging in Costa Rica’s well-known longevity hotspot. The session highlights both biological vulnerability and resilience in response to psychosocial and environmental exposures.

Maleah Fekete | Indiana University

The Role of Stress Proliferation in Linking Adverse Childhood Experiences to Accelerated Biological Aging


Shaimaa Elrefaay | UC San Francisco

Epigenetic and Transcriptomic Profiles of Immune, Inflammatory, and Cellular Transduction Pathways Are Associated With Severe and Chronic Perceived Stress in Midlife Women


Brooke McKenna | Purdue University | Massachusetts General Hospital

Childhood Exposure to Violence: Associations with DNA Methylation in a South African Birth Cohort


Leland Fleming | McLean Hospital | Harvard Medical School

Epigenetic Mirroring Between Mothers and Infants: The Intergenerational Impact of Early Life Adversity

Hannah-Ruth Engelbrecht | University of British Columbia

A lack of time – no evidence of reduced epigenetic age acceleration in the longevity hot spot of Costa Rica within the Costa Rican Longevity and Healthy Aging Study